Primary hyperparathyroicism is a state of hypersecretion of PTH by the parathyroid. The etiology has not been established. The three possible etiologies of primary hyperparathyroidism and incidences are adenoma(83%), hyperplasia(15%), and
carcinoma(1~2%). Parathyroid carcinoma usually presents in the fourth decades. The hallmark preoperative signs are hypercalcemia(serum calcium >mg/dl). Palpable neck mass and bone and renal disease. Patients may present with multiple signs and
symptoms.
including recurrent nephrolithiasis, peptic ulcers, mental change, less frequently, extensive bone resorption. However, with greater awareness of the disease and wider use of screening tests, including blood calcium determinations, the diagnosis
is
frequently made in patients who have no symptoms and minimal, if any, signs of the disease other than hypercalcemia and elevated levels of parathyroid Hormone. An 38-years-old woman was admitted to the hospital due to pain on the left knee joint.
We
experienced full-brown symptom pertaining to hyperparathyroidism. Thus we report a case herein and also discuss clinical manifestation, histologic features and treatment(J Kor Soc Endocrinol 11 : 221~226, 1996).
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